Neurovascular degeneration is a common feature of vision disorders such as diabetic retinopathy, optic neuritis and retinopathy of prematurity. Goal of my laboratory is to contribute towards the development of novel therapeutic strategies for these pathologies, through characterizing the mechanisms regulating retinal neurovascular damage. Our current research is focused on investigating the role of polyamine oxidase signaling pathways in causing neurodegeneration and vascular injury in the retina.
Mechanisms of neurovascular damage in diabetic retinopathy
Neuro-glial and vascular interactions in ischemic retinopathy models
Molecular mechanisms causing visual dysfunction in Multiple Sclerosis