The primary focus of his research is on the elucidation of the peripheral mechanisms involved in analgesia associated with inflammation. The focus extends from molecular mechanistic based studies through to studies involving therapeutic outcomes in patients with whiplash, burns and back injury.
Key discoveries were made in this field that highlighted the importance of the immune system in inflammatory pain. The results of which were published in the notable journals; Nature Medicine, JBC and The Journal of Clinical Investigation. These studies have been presented both at international pain meetings and at the Australasian Society for Clinical and Experimental Pharmacology and Toxicology.
More recently notable advances have been made in the understanding of the metabolic production of fragments of the opioid peptide family as well as insights into novel mechanisms in the opioidergic system