Harmacogenetics/Pharmacogenomics - I am interested in identifying genetic targets for both treatment response as well as adverse drug reactions. With the advancement of genetic technologies and the reduction in costs for genetic projects, it is fast becoming a reality to do these projects within a reasonable time frame and budget. The implications of these projects will revolutionise the way doctors prescribe drugs for their patients.
Genetics of human disease - We have now come to understand that complex diseases are multigenic and as we find out more about the genetic make up of humans, indirectly we are also finding out more about the genetics of diseases. This information is useful in designing new drug targets.
Currently I have research collaborations with the drugs of abuse group looking at the genetics of addiction to prescriptive opioids in non-cancer based chronic pain. I am also collaborating with the epilepsy group within the School of Pharmacy trying to work out response markers for anti-epiletic drugs.
In collaboration with Dr Catherine King and Dr Michael Wiese, I am providing genotyping service using the ABI 7500 Fast machine. This service is available to researchers within as well as outside the University